News Letter

At 63, maintaining 7% body fat taught me something most people never grasp: excess body fat isn’t just storage—it’s an active metabolic weapon systematically dismantling your cardiovascular infrastructure. The 2024 European Heart Journal analysis of over 10 million people confirmed what I discovered through rigorous self-experimentation: every incremental 10-pound increase in body fat initiates a quantifiable cascade of inflammatory damage, insulin resistance, and cardiovasc

If you’ve been told you have Hashimoto’s thyroiditis—or suspect you might—you’re not alone. Hashimoto’s is the most common autoimmune disease in the world and the leading cause of hypothyroidism in developed countries. It occurs when the immune system mistakenly targets the thyroid gland, gradually damaging the tissue responsible for producing thyroid hormone. An estimated 5–10% of the population has Hashimoto’s, with women affected 7–10 times more often than men . Even more

W hat does the latest human research really tell us about metabolic health and cognitive aging? For decades, the prevention of cognitive decline has focused almost entirely on the brain itself. Alzheimer’s disease and related dementias were framed as isolated neurological conditions driven by amyloid plaques, tau tangles, and neuronal loss. While these mechanisms remain essential, a growing body of human research suggests that this brain-only model is incomplete. Increasingly

Why Your Brain Doesn’t Care About Your New Year’s Resolution—But Your Identity Does As we move toward the New Year, most people start talking about “getting motivated.” New gym memberships, latest supplements, new planners, new promises. But here’s the uncomfortable truth: Motivation is a myth. At least in the way most people think about it. Your success in 2026 will not depend on motivation. It will depend on identity. And the science is finally catching up to what many tran

Your heart's rhythm holds the secret to your longevity—and most people are measuring the wrong thing. The Science Spotlight: Your Weekly Deep Dive Into Breakthrough Research I spent decades in believing that a low resting heart rate was the gold standard for cardiovascular fitness. I've learned that the real marker of physiological resilience isn't how slow your heart beats—it's how adaptable it is. Heart Rate Variability, or HRV, measures the variation in time between consec

There is no proven casual link between melatonin and heart failure. By Dr. Travis Smith, DO – Bio Precision Aging Medical Editorial Team A recent analysis presented at the American Heart Association (AHA) Scientific Sessions 2025 sparked headlines suggesting that long-term melatonin use may increase the risk of heart failure. But before we draw conclusions, it’s critical to understand what the study actually showed—and what it did not prove. Let’s unpack the findings, the li

By Travis Smith, DO A s physicians working in precision aging and longevity medicine, we’re constantly seeking evidence-based interventions that can meaningfully impact healthspan and lifespan. Recent landmark research from major academic institutions has revealed something remarkable: daily low-dose tadalafil may be one of the most underutilized longevity interventions available today. The Numbers Are Staggering A comprehensive study published in The Journal of Sexual Medic

Your cholesterol might be perfect, but if your hsCRP is above 3 mg/L, your risk of early death just tripled. This blood marker that 90% of people never test could be the difference between thriving at 80 or struggling at 60. A fter decades of monitoring every biomarker I could get my hands on, I've learned that the numbers that matter most aren't always the ones we're watching. Sure, everyone tracks cholesterol and blood sugar. But there's one marker that's been quietly predi

What follows is a guide to discussing testosterone with your physician, what labs to monitor, what adjunctive therapies to consider, and what the trade-offs are. Testosterone & Aging: More Than Just One Hormone When people talk about testosterone (T) and “anti-aging,” there’s often an oversimplified narrative: “My T is low → I’ll take exogenous testosterone → I’ll feel better, live longer.” The reality is more nuanced. Testosterone is one node in a complex endo­crine network.

By Dr. Jackson Taylor, PT, DPT, CPS, Contributor I've been seeing 3x10 since I was a freshman in high school. It has been the prescription in football weight rooms, the cookie-cutter sets plastered on bodybuilding magazines, and even the default dosage they drilled into us in Physical Therapy school. And while it's not "wrong," it's lazy. It's an easy, off-the-tongue statement—simple to remember, simple to prescribe. That's why it has survived. The Truth Muscle doesn't care a

By Dr. Jackson Taylor, PT, DPT, CPS, Contributor Shoulder pain is one of the most common musculoskeletal complaints, with nearly 70% of adults experiencing it at some point in life (Luime et al., 2004). But here's the catch: pain and structural damage don't always match up. Some men have MRI scans that look like a grenade went off in their shoulder yet feel fine. Others show little or no damage on imaging but are crippled by pain. Pain Without Damage Multiple studies show th

Think osteopenia means you're too fragile to lift heavy weights? New research proves the opposite - high-intensity training can actually reverse bone loss and prevent fractures. The game-changing LIFTMOR study shows how. At 63, I've learned that our bones tell a story - one of resilience, adaptation, and the remarkable capacity for renewal when we give them the right signals. Today, I want to share groundbreaking discoveries about osteopenia that challenge everything we thoug

Insulin: Friend, Foe, or Just Misunderstood? By Dr. Jackson R. Taylor | Contributing Author In the world of precision aging, few hormones are as simultaneously essential and potentially destructive as insulin. While this pancreatic powerhouse keeps us alive moment by moment, its dysregulation may be silently accelerating our biological clock. Understanding insulin's dual nature—and learning to optimize it—could be one of the most impactful interventions in your longevity too

The Essential Guide to Muscle Growth and Lasting Strength By Dr. Jackson Taylor, PT, DPT, CPS | Bio Precision Aging Contributor The Essential Guide to Muscle Growth and Lasting Strength By Dr. Jackson Taylor, PT, DPT, CPS | Bio Precision Aging Contributor I've been in the gym most of my life—first as an athlete, later as a coach and clinician, and now as a husband and dad. And one thing I can tell you without hesitation: building muscle has changed everything for me. It's not

While everyone's talking about creatine for muscle gains, groundbreaking 2024 research reveals its most powerful benefit might be protecting your brain and enhancing cognitive function as you age. The secret? Your brain burns 20% of your daily energy—and creatine is its preferred fuel source. After decades in the fitness world and fifteen years of following anti-aging protocols, I thought I knew everything about creatine. I was wrong. While the supplement aisle buzzes with ta

Consistent Exercise, Nutrition, and Sleep Represent the Trinity of Longevity I've noticed a consistent pattern in my conversations about health and wellness: people jump straight to the bells and whistles while ignoring the foundation. Whether it's the latest supplement stack, cold plunge protocols, infrared saunas, or which fitness tracker provides the most accurate HRV readings, these questions typically come from individuals who haven't mastered—or sometimes even started—t

Clinical trials prove berberine matches metformin's glucose control while slashing cholesterol by 29 percent and triglycerides by 35 percent - without prescription side effects . On my 16 year journey to optimizing my health through evidence-based interventions, I have encountered countless natural compounds claiming miraculous benefits. However, few have impressed me as much as berberine, a golden-yellow alkaloid that has emerged from traditional Chinese medicine to become

New clinical research reveals that 30 milliliters of apple cider vinegar daily can slash hemoglobin A1C levels by 0.50 percent while dramatically improving cholesterol profiles in just 8 weeks. Throughout my journey to transform my health through evidence-based protocols, I have encountered countless supplements and interventions promising miraculous results. However, few have surprised me as much as the emerging science behind apple cider vinegar and its profound metabolic

Revolutionary research reveals that 1 gram of omega-3 daily can turn back your biological clock. The fountain of youth might be swimming in our oceans. Over the last 15 years curiosity has fuel my fitness journey.  I am constantly amazed by breakthrough discoveries that validate what many of us in the precision health community have suspected for years. The latest research on omega-3 fatty acids represents one of the most significant advances in our understanding of how nutr

The moderate-intensity exercise protocol that's transforming mitochondrial health, metabolic flexibility, and longevity for high-performers worldwide. The Science Spotlight Y our weekly deep dive into breakthrough research As someone who has spent over a decade optimizing my health through evidence-based protocols, I've witnessed countless fitness trends come and go. However, the recent explosion of research surrounding Zone 2 training represents something fundamentally diffe