At 63, maintaining 7% body fat taught me something most people never grasp: excess body fat isn’t just storage—it’s an active metabolic weapon systematically dismantling your cardiovascular infrastructure. The 2024 European Heart Journal analysis of over 10 million people confirmed what I discovered through rigorous self-experimentation: every incremental 10-pound increase in body fat initiates a quantifiable cascade of inflammatory damage, insulin resistance, and cardiovasc

Wichman et al. (2016) published a landmark meta-analysis in Thyroid , examining six randomized controlled trials with 463 participants diagnosed with Hashimoto’s thyroiditis and elevated TPO antibodies.   The Discovery:   Pooled analysis demonstrated selenium supplementation produced a weighted mean reduction of 123.6 IU/mL in TPO antibody levels compared to placebo (95% CI: -234.5 to -12.7, p=0.029). For context, this represents a 26-36% average reduction depending on basel

W hat does the latest human research really tell us about metabolic health and cognitive aging? For decades, the prevention of cognitive decline has focused almost entirely on the brain itself. Alzheimer’s disease and related dementias were framed as isolated neurological conditions driven by amyloid plaques, tau tangles, and neuronal loss. While these mechanisms remain essential, a growing body of human research suggests that this brain-only model is incomplete. Increasingly